INTERSTITIAL PERFUSION CULTURE WITH SPECIFIC SOLUBLE FACTORS INHIBITS TYPE I COLLAGEN PRODUCTION FROM HUMAN OSTEOARTHRITIC CHONDROCYTES IN CLINICAL-GRADE COLLAGEN SPONGES.

Articular cartilage has poor healing ability and cartilage injuries often evolve to osteoarthritis.Cell-based strategies aiming to engineer cartilaginous tissue through the combination of biocompatible scaffolds and articular chondrocytes represent an alternative to standard surgical techniques.In this context, perfusion bioreactors have been intro

Physical cues are major determinants of cellular phenotype and evoke physiological and pathological responses on cell structure and function.Cellular models aim to recapitulate basic functional features of their in vivo counterparts or tissues in order to be of use in in vitro disease modeling wacoal 36h or drug screening and testing.Understanding

The effect of Ca and Sr-doping on the structural electronic and optical properties of the cubic Ba1-xCaxTiO3 and Ba1-xSrxTiO3 (x=0.4, 0.6) mixed crystals was investigated using first-principles calculations based on density bodega de san antonio sangria functional theory (DFT).The calculated band structures based on the optimized geometry of the ce